Resources

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Tang, L., Zirpoli, G.R., Guru, K., Moyisch, K.B., Zhang, Y., Ambrosone, C.B., McCann, S.E. (2008). "Consumption of raw cruciferous vegetables is inversely associated with bladder cancer risk." Cancer Epidemiology, Biomarkers & Prevention 17(4): 938-944.

Kirsh, V. A., U. Peters, et al. (2007). "Prospective study of fruit and vegetable intake and risk of prostate cancer." Jounal of the National Cancer Institute 99(15): 1200-1209.

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Fowke, J. H., C. Longcope, et al. (2000). "Brassica vegetable consumption shifts estrogen metabolism in healthy postmenopausal women." Cancer Epidemiology, Biomarkers & Prevention 9: 773-779.

Ambrosone, C. B., S. E. McCann, et al. (2004). "Breast cancer risk in premenopausal women is inversely associated with consumption of broccoli, a source of isothiocyanates, but is not modified by GST genotype." Nutrition and Cancer 134: 1134-1138.

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Seow, A., J.-M. Yuan, et al. (2002). "Dietary isothiocyanates, glutathione S-transferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study." Carcinogenesis 23(12): 2055-2061.

Zhao, B., A. Seow, et al. (2001). "Dietary isothiocyanates, glutathione S-transferase-M1, -T1 polymorphisms and lung cancer risk among Chinese women in Singapore." Cancer Epidemiology, Biomarkers & Prevention 10: 1063-1067.

Brennan, P., C. C. Hsu, et al. (2005). "Effect of cruciferous vegetables on lung cancer in patients stratified by genetic status: a Mendelian randomisation approach." The Lancet 336: 1558-1560.

Zhao, H., J. Lin, et al. (2007). "Dietary isothiocyanates, GSTM1, GSTT1, NAT2 polymorphisms and bladder cancer risk." International Journal of Cancer 120(10): 2208-2213.

Kensler, T. W., J.-G. Chen, et al. (2005). "Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflotoxin-DNA adducts and phenanthrene tetraols in a randomised clinical study in He Zuo township, Qidong, Peoples Republic of China." Cancer Epidemiology, Biomarkers & Prevention 14: 2605-2613.

Steinmetz, K. A. and J. D. Potter (1996). "Vegetables, fruit and cancer prevention: a review." Journal of the American Dietetic Association 96(10): 1027-1039.

Sapone, A., A. Affatato, et al. (2007). "Cruciferous vegetables and lung cancer." Mutation Research 635: 146-148.

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London, S. J., J.-M. Yuan, et al. (2000). "Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms and lung cancer risk: a prospective study of men in Shanghai, China." The Lancet 356: 724-729.

Voorrips, L. E., R. A. Goldbohm, et al. (2000). "Vegetable and fruit consumption and risks of colon and rectal cancer in a prospective cohort study: The Netherlands Cohort Study on diet and cancer." American Journal of Epidemiology 152(11): 1081-1092.

Farnham, M. W., K. K. Stephenson, et al. (2000). "Capacity of broccoli to induce a mammalian c hemoprotective enzyme varies among inbred lines." Journal American Society Horticultural Science 125(4): 482-488.

Talalay, P. and J. W. Fahey (2001). "Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism." Journal of Nutrition 131(11): 3027S-3033S.

Prestera, T. and P. Talalay (1995). "Electrophile and antioxidant regulation of enzymes that detoxify carcinogens." Proceedings of the National Academy of Science USA 92(19): 8965-8969.

Munday, R. and C. M. Munday (2004). "Induction of Phase II detoxifying enzymes in rats by plant-derived isothiocyanates: Comparisons of allyl isothiocyanates with sulfuraphane and related compounds." Journal of Agricultural and Food Chemistry 52: 1967-1871.

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Posner, G. H., C.-G. Cho, et al. (1994). "Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes." Journal of Medical Chemistry 37: 170-176.

Wettasinghe, M., B. Bolling, et al. (2002). "Screening for phase II enzyme-inducing and antioxidant activities of common vegetables." Journal of Food Science 67(7): 2583-2588.

Vang, O., H. Frandsen, et al. (2001). "Biochemical effects of dietary intakes of different broccoli samples. I. Differential modulation of cytochrome P-450 activities in rat liver, kidney, and colon." Metabolism: Clinical & Experimental 50(10): 1123-1129.

Matusheski, N. V. and E. H. Jeffery (2001). "Comparison of the bioactivity of two glucoraphanin hydrolysis products found in broccoli, sulforaphane and sulforaphane nitrile." Journal of Agricultural Food Chemistry 49: 5743-5749.

Zhang, Y. S., R. Munday, et al. (2006). "Induction of GST and NQO1 in cultured bladder cells and in the urinary bladders of rats by an extract of broccoli (Brassica oleracea italica) sprouts." Journal of Agricultural and Food Chemistry 54(25): 9370-9376.

Dinkova-Kostova, A. T., J. W. Fahey, et al. (2007). "Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts." Cancer Epidemiology, Biomarkers & Prevention 16(4): 847-851.

Petri, N., C. Tannergren, et al. (2003). "Absorption/metabolism of sulforaphane and quercetin, and regulation of phase II enzymes, in human jejunum in vivo." The American Society for Pharmacology and Experimental Therapeutics 31(6): 805-813.

Keck, A.-S., Q. Qiao, et al. (2003). "Food matrix effects on bioactivity of broccoli-derived sulforaphane in liver and colon of F344 rats." Journal of Agricultural and Food Chemistry 51(11): 3320-3327.

Steinkellner, H., S. Rabot, et al. (2001). "Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens." Mutation Research, Fundamental and Molecular Mechanisms of Mutagensis 480/481: 285-297.

Ritz, S. A., J. X. Wan, et al. (2007). "Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract." American Journal of Physiology 292(1): L33-L39.